Basic science: (December 2005)

DDT December 2005.qxp

1689 www.drugdiscoverytoday.com The first attempts at global analysis of gene expression were undertaken in the mid-1970s with studies of the hybridization of an mRNA pool with radioactively labeled cDNA. Interest in gene expression increased steadily during the 1980s, and in the 1990s a new era of high throughput gene expression studies unfolded with the development of microarrays [1,2]. Altho...

London, 14 December 2005

DDT December 2005.qxp

1697 www.drugdiscoverytoday.com Although early detection of pathology can greatly improve patient outcomes, there are relatively few good noninvasive molecular tools for diagnosis of early-stage disease, such as premalignant cancer [1,2], or for prognosis, such as identifying cardiac patients at higher risk of dying (e.g. the Framingham Heart Study), or of non-responsiveness to therapy [3]. The...

FSTTCS 2005: Foundations of Software Technology and Theoretical Computer Science, 25th International Conference, Hyderabad, India, December 15-18, 2005, Proceedings

One day, you will discover a new adventure and knowledge by spending more money. But when? Do you think that you need to obtain those all requirements when having much money? Why don't you try to get something simple at first? That's something that will lead you to know more about the world, adventure, some places, history, entertainment, and more? It is your own time to continue reading habit....

Separating "focus Movement" from Focus (december 2005)

Movement operations in the Minimalist Program (MP) framework are assumed to be last resort, that is, to have to be driven by some interface need. In recent versions of the MP (Chomsky 2000, 2004), movement has been viewed as a concomitant of the operation 'Agree', under which a head bearing an uninterpretable (unvalued) instance of a formal feature F, acting as Probe, seeks to enter into a feat...